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what is priligy dapoxetine Consistent with our previous data that SMC Klf4 and SMC Oct4 knockout have opposite phenotypes in terms of lesion morphology and cell composition, gene set enrichment analysis of bulk RNA seq data using the MSigDb showed 70 of the down regulated hallmark and Kyoto Encyclopedia of Genes and Genomes pathways in SMC Klf4 О” О” versus SMC Klf4 WT WT were up regulated in SMC Oct4 О” О” versus SMC Oct4 WT WT, and nearly all up regulated pathways in SMC Klf4 О” О” versus SMC Klf4 WT WT were down regulated in the SMC Oct4 knockout model Figure 1A 1C, Figure II in the Data Supplement
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